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Journal: bioRxiv
Article Title: Pooled CRISPRi screening reveals fungal-specific vulnerabilities across environments and genetic backgrounds
doi: 10.64898/2025.12.19.695556
Figure Lengend Snippet: a) Single nucleotide polymorphisms (SNPs) detected by whole genome sequencing for the three strains when compared to the SC5314 reference genome. b) Overlap between sgRNAs with target binding regions affected by SNPs. The lower left histogram shows the total number of sgRNAs affected for each strain.
Article Snippet:
Techniques: Sequencing, Binding Assay
Journal: Journal of Clinical Microbiology
Article Title: A standardized, genome-guided MLST scheme for Avibacterium paragallinarum : enhanced epidemiological typing and validation against existing methods
doi: 10.1128/jcm.01267-25
Figure Lengend Snippet: Clustering of the A. paragallinarum samples based on cgMLST. ( A ) Minimum spanning tree based on the allelic profiles of 1,170 core gene targets from 57 whole-genome samples using the SeqSphere+ software. ( B ) cgMLST dendrogram displaying 57 whole genome-sequenced A. paragallinarum samples. The distance matrix was built from all pairwise allelic profile comparisons of 1,170 cgMLST targets using the missing values as an own category option in SeqSphere+ software . Samples are color-coded by geographic origin, and dendrograms are rooted by the AP08_SA.
Article Snippet: A total of 75 A. paragallinarum samples were used in the study, consisting of 45
Techniques: Software
Journal: Journal of Clinical Microbiology
Article Title: A standardized, genome-guided MLST scheme for Avibacterium paragallinarum : enhanced epidemiological typing and validation against existing methods
doi: 10.1128/jcm.01267-25
Figure Lengend Snippet: Minimum spanning tree of whole genome-sequenced samples based on two MLST profiles color-coded based on their geographic origin. ( A ) Minimum spanning tree of the WGS samples created using the seven-locus MLST scheme described by Guo et al. . ( B ) Minimum spanning tree of the WGS samples created using the MLST scheme developed in this study.
Article Snippet: A total of 75 A. paragallinarum samples were used in the study, consisting of 45
Techniques: